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Issue Brief
Antibiotic Innovation: The Threat and the Pipeline
The Superbug Threat explores the emergence of antibiotic-resistant bacteria and its impact on human health, as well as the shrinking pipeline of new antibiotics.
This bibliography lists the latest published scientific and economic literature concerning the contribution of routine antibiotic use in food animals to the growing public health crisis of human antibiotic resistance. Research on how antibiotic use in food animal production contributes to the growing health crisis of antibiotic resistance dates back more than 30 years.
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As multidrug-resistant infections have grown more prevalent, few new antibiotics are reaching the market. This is attributed, in part, to the economic and regulatory challenges associated with their development. Recently, stakeholders have endorsed a novel regulatory pathway to approve these lifesaving drugs for use in limited patient populations — namely those at highest risk and with few or no other options.
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"As a nation, we need to exercise greater care with our use of antibiotics, in both humans and animals, so that these medications remain effective in treating serious bacterial infections."
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SuperChefs Against Superbugs, an initiative of the Pew Campaign on Human Health and Industrial Farming, is a movement of chefs nationwide who have expressed their support of ending the misuse and overuse of antibiotics in food animal production. As a result, the SuperChefs are urging the Food and Drug Administration to strengthen its antibiotic policies.
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It used to be easy to treat healthy children with common bacterial infections; a regimen of antibiotic pills could usually wipe out the disease. Today, patients might need to go home on intravenous antibiotics because oral therapies will no longer work. Antibiotic resistance is to blame.
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